Download Citation on ResearchGate | Cancer de la ampolla de Vater | The authors report the results of studies on five patients -3 males and 2 females- with . Periampullary tumors are neoplasms that arise in the vicinity of the ampulla of Vater. Neoplasms that arise in this site can originate from the. Metastasis of breast cancer to major duodenal papilla Palabras clave: Ampolla de Vater; Neoplasias de la mama; Ictericia (fuente: DeCS BIREME).

Author: Tosar Akinocage
Country: Bolivia
Language: English (Spanish)
Genre: Medical
Published (Last): 5 February 2011
Pages: 490
PDF File Size: 19.35 Mb
ePub File Size: 12.41 Mb
ISBN: 762-5-68973-502-4
Downloads: 39117
Price: Free* [*Free Regsitration Required]
Uploader: Keran

Impact of postoperative irradiation after non-curative resection of hilar biliary cancer.

The laboratory evaluation revealed bilirubin totals 7. Polypoid tumors of the major duodenal papilla: Median survival was A phase III multicenter prospective randomized controlled trial in patients with resected pancreaticobiliary carcinoma. Tumors of the ampulla of vater: Neoplastic diseases of the papilla of Vater. The double duct sign. The efficacy of a gemcitabine-based as compared to a 5FU-based adjuvant vager was also emphasized by another trial, in which chemotherapy for 3 wk prior and for 12 wk after CCRT was administered[ 50 ].

Conclusion Although metastases of breast carcinomas are infrequent to the gastrointestinal tract, neoplasms of the juxtapapillary region should be suspected, especially at an early stage, since curative resection can be offered.

Metástasis del cáncer de mama a la papila mayor duodenal

Registry data collection variables. The Ampulla of Vater is a flasklike cavity into which both the common bile and pancreatic ducts open. Immunohistochemistry plays a key role for indicating the histological type of the tumor, since the metastases of lobular breast carcinoma to the gastrointestinal tract have an endoscopic, radiological and histological aspect similar to the adenocarcinoma poorly differentiated with signet ring cells.

Carcinomas of the Ampulla of Vater are rare tumors, accounting for 0. In particular, we analyzed demographic characteristics, tumor histology, UICC stage, treatments employed and survival time for consecutive ampullary and biliary tract carcinoma patients.

Neoplasms of the ampulla of vater with concurrent pancreatic intraductal neoplasia: The concept of ampullary carcinoma as a distinct entity is challenged by the categorization of dd into intestinal type and biliopancreatic type histologically. Biology portal Medicine vqter. Carcinoma of the Ampulla of Vater.


Tumors of ampulla of Vater: A case series and review of chemotherapy options

Surgical management of neoplasms of the ampulla of Vater: Neoplasms that arise in this site can originate from the. Preoperative biliary drainage in jaundiced patients is indicated in patients ampo,la cholangitis and those with profound hyperbilirubinemia as cancer de ampolla de vater may impact coagulation status and wound healing.

Surgery represents the main therapeutic approach for ampullary cancer, whilst unresectable tumors can be treated with either radiotherapy or chemotherapy. None of the authors have any conflict of interests to disclose. There is no standard chemotherapeutic regimen for metastatic disease. Lost of follow-up; OS: The cystic duct leaves the gallbladder and joins with the common hepatic duct to form the common bile duct.

It was first described in the British Medical Journal by Dr. The patient underwent an endoscopic retrograde cholangiopancreatography ERCPwhere a swollen, friable and bleeding papilla was found, with necrotic areas. Radiotherapy alone has been tested in patients with extrahepatic bile duct carcinoma in only a few studies, and with conflicting results[ 31 – 33 ]. Intestinal ampullary adenocarcinomas originate from the intestinal epithelium overlying the ampulla whereas pancreaticobiliary ampullary carcinomas originate from the epithelium of the distal common bile duct and distal pancreatic duct.

Overall, patients with ampullary carcinoma showed a significantly higher median survival than those patients with other biliary tumors 22 mo vs Is endosonography an effective method for detection and local staging of the ampullary carcinoma? Locally advanced and metastatic disease Surgery represents the main therapeutic approach for ampullary cancer, whilst unresectable tumors can be treated with either radiotherapy or chemotherapy.

Am J Surg Pathol. Died of other cause; LOF: Conversely, no survival advantage was reported between patients with pancreatic, bile duct, or ampullary carcinomas. Extensive preoperative assessment of cardiac, vaher, renal, and cerebral functions should be performed in older patients or those with comorbid conditions. Based on their epithelium of origin, two subtypes of ampullary carcinoma have been recently distinguished: Cancers of the ampulla of vater: Int J Surg Case Rep.


In this report we present a case of biliary obstruction due to metastatic breast cancer to the major duodenal papilla. The median age at diagnosis was 64 years range: The efficacy of frontline platinum-based combination chemotherapy in advanced adenocarcinoma of the ampulla of Vater.

Ampulla of Vater carcinoma in real-world clinical practice: Histological examination showed a carcinoma, with infiltration in the duodenal mucosa.

Conversely, no survival advantage was reported between patients with pancreatic, bile duct, or ampullary carcinomas. We report a case of obstructive jaundice due to a metastatic breast carcinoma to the major duodenal papilla, and assess curative and palliative treatment that interventional endoscopy can offer.

In cases of invasive tumors, duodenopancreatectomy is the treatment canfer choice. Factors predictive of survival in ampullary carcinoma. An endoscopic ultrasound EUS was recommended, and it demonstrated infiltration of the injury until the muscular layer of the duodenal wall, without suspicious regional lymph nodes.

Predictors for patterns of failure after pancreaticoduodenectomy in ampullary cancer. One possible cause of impaired drainage of pancreatic juice is blockage of the sphincter of Oddi.

Skip to content Home.


Clinically, however, ampullary tumors can be virtually indistinguishable ajpolla tumors of the distal bile duct or pancreatic head; the point of origin of tumors in this region is typically not determined until the patient undergoes surgery.

This is mostly because of the small size of the ampulla of Vaterand flat mucosal lesions are ampoola replaced by invasive carcinoma in most surgically resected specimens.

Diseases of the biliary tract and the papilla of Vater in Keichi Kawai.